Bioavailability and bioefficacy of folate and folic acid in man

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Bioavailability and bioefficacy of folate and folic acid in man.

Folic acid is important because supplementation around the time of conception has been proven to lower the risk of having offspring with a neural-tube defect. Furthermore, both dietary folate and folic acid decrease plasma total homocysteine concentrations. Elevated plasma homocysteine concentrations are considered to be an independent risk factor for cardiovascular disease. The aim of the pres...

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Effect of Dietary Betaine and Folic Acid Supplementation on Performance, Egg Folate Content and Egg Production of Japanese Quail

A study was conducted to investigate the effects of different betaine (BET) (0.0, 0.5 or 1.0 g/kg) and folic acid (FA) (0.0, 4.0 or 8.0 mg/kg) levels on performance, egg FA concentration and egg production of laying quails using 288 forty-two day-old Japanese quail in a 3 × 3 factorial arrangement of treatment based on randomized complete design. The results showed that none of the performance ...

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synthesis of sulfides from alcohols and thiols in solvent-freeconditions and deoxygenation of sulfoxides

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Folic acid and folate binding protein in pregnancy.

Folic acid and folate binding protein (FABP) concentrations were determined in 208 pregnant women as well as in 50 non-pregnant women. Serum folate levels in pregnant women were significantly lower than those of the non-pregnant group. Anaemic pregnant women also had lower serum folate concentrations than those of the non-anaemic pregnant women. Ninetyeight of 208 (47.1%) pregnant women had ser...

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Bioavailability of heptaglutamyl relative to monoglutamyl folic acid in healthy adults.

BACKGROUND The bioavailability of dietary folate has been estimated to be approximately 50% of that of synthetic folic acid. Folate in the diet is linked to a polyglutamate chain that may restrict folate absorption. OBJECTIVE Our goal was to quantify the bioavailability and bioefficacy of low doses of polyglutamyl folic acid relative to that of monoglutamyl folic acid. DESIGN In total, 180 ...

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ژورنال

عنوان ژورنال: Nutrition Research Reviews

سال: 2001

ISSN: 0954-4224,1475-2700

DOI: 10.1079/095442201108729240